Progeria is a very rare genetic illness where symptoms including aspects of aging are shown at a really young age. Progeria is just one of many progeroid syndromes. Those born with progeria normally reside for their mid-teens to early twenties. It's a hereditary condition which occurs as a brand new mutation, also is seldom inherited, as carriers normally do not live to replicate. Even though the expression progeria applies strictly talking to most diseases characterized by premature aging signs, and is frequently employed as such, it's frequently implemented specifically with regard to Hutchinson--Gilford progeria syndrome (HGPS).
Progeria (pro-JEER-e-uh), also called Hutchinson-Gilford syndrome, can be a very rare, progressive genetic disorder that causes children to age quickly, beginning in their first two years of life.

Children with progeria generally seem normal at birth. Throughout the initial year, symptoms and signs, such as slow growth and baldness, start to appear.

Heart problems or strokes would be the ultimate cause of death in many children with progeria. A few with the disorder can die younger and others might survive longer, even up to 20 years.

There is no treatment for progeria, but continuing research reveals some promise for therapy.

Symptoms

Normally within the first year of life, growth of a child with progeria slows markedly, but motor development and brains stay normal.

Symptoms and signs of the progressive disorder comprise a distinguishing look:

Hair loss, including eyelashes and eyebrows
Thinning, spotty, wrinkled skin
Visible veins
High-pitched voice
Slowed growth, with below-average height and weight
Narrowed face, small lower jaw, thin lips and beaked nose
Head disproportionately large for the face
Prominent eyes and incomplete closure of the eyelids
High-pitched voice
Signs and symptoms also include health issues:

Severe progressive heart and blood vessel (cardiovascular) disease
Hardening and tightening of skin on the trunk and extremities (similar to scleroderma)
Delayed and abnormal tooth formation
Some hearing loss
Loss of fat under the skin and loss of muscle mass
Skeletal abnormalities and fragile bones
Stiff joints
Hip dislocation
Insulin resistance

Causes

A single gene mutation accounts for progeria. The gene, called lamin A (LMNA), makes a protein required for holding the center (nucleus) of a cell together. If this gene has a defect (mutation), an abnormal type of the lamin A protein called progerin is generated and creates cells shaky. This seems to result in progeria's aging procedure.

Unlike a lot of genetic mutations, progeria is rarely handed down in families. The gene mutation is a rare, opportunity occurrence in the vast majority of instances.

Other similar syndromes

There are other progeroid syndromes that do run in families. These inherited syndromes cause rapid aging and a shortened life span:

Wiedemann-Rautenstrauch syndrome, also known as neonatal progeroid syndrome, starts in the womb, with signs and symptoms of aging apparent at birth.
Werner syndrome, also known as adult progeria, begins in the teen years or early adulthood, causing premature aging and conditions typical of old age, such as cataracts and diabetes.


Source: https://aderonkebamidele.com/progeria-causes-prevention/